Wednesday, March 23, 2011

Life-threatening emergencies:essential knowledge

essential knowledge
Weight: (1 kg = 2·2 lb)
Infant: 0–1 years = 3–10 kg
5 months: double birth weight
12 months: treble birth weight
After 1 year: wt in kg = 2 (age + 4)
2 years: quadruple birth weight.
Airway and breathing (endotracheal
intubation) under 25 kg = uncuffed
Full term infant = 3·0–3·5 mm ID
Infant < 1 year = 4·0–4·5 mm ID
Child > 1 year = age/4 + 4 ID.
                   Age + 12 cm for oral tube
Length of tube =
                     2+ 14 cm for nasal tube

Circulation (dehydration treatment: deficit in
ml = % dehydration × weight in kg × 10)
Blood pressure systolic = 80 + (age year × 2) Cuff must be
  two-thirds size of upper arm and the largest that will fit
Capillary refill = 2 seconds or less after 5 seconds pressure
  (sternum)
Drip rates for clear fluids: (standard giving set)
  20 drops = 1 ml
  ml/h divided by 3 = drops/min
Minimum urine output: > 1 ml /kg/h in children, > 2 ml/kg/h
  in infants
12 ml /kg/24 h if > 1 year
15 ml/kg/24 h if an infant
24 ml /kg/24 h if preterm
increased if in hot climate by around 50%
increased if fever by 50%
Fluid management
Blood volume is 100 ml/kg at birth falling to 80 ml/kg at
1 year. Total body water varies from 800 ml/kg in the neonate
to 600 ml/kg at one year and thereafter. Of this about two
thirds (400 ml/kg) is intracellular. Clinically, dehydration is
not detectable until >5% (50 ml/kg).


Insensible losses: 300 ml/m2/24 h or


12 ml /kg/24 h if > 1 year
15 ml/kg/24 h if an infant
24 ml /kg/24 h if preterm
increased if in hot climate by around 50%
increased if fever by 50%

Fluid management
Blood volume is 100 ml/kg at birth falling to 80 ml/kg at
1 year. Total body water varies from 800 ml/kg in the neonate
to 600 ml/kg at one year and thereafter. Of this about two
thirds (400 ml/kg) is intracellular. Clinically, dehydration is
not detectable until >5% (50 ml/kg).
Fluid requirements:
Replace insensible losses through sweat, respiration,
gastrointestinal loss etc.
Replace of essential urine output, the minimal urine output
to allow excretion of the products of metabolism etc.
Extra fluid to maintain a modest state of diuresis.
Fluid to replace abnormal losses such as blood loss,
severe diarrhoea, diabetic polyuria losses etc.

Essential drug doses

Aminophylline: IV loading dose 5 mg/kg over 20 minutes
  (max = 250 mg) then 1 mg/kg/h by IV infusion
Benzyl penicillin: 50 mg/kg IV 4–6 hourly
Cefotaxime: IV 50 mg/kg 6 hourly
Diazepam IV or IO 100–250 micrograms/kg or rectal 500
  micrograms/kg (max = 10 mg)
Lorazepam IV or IO 50–100 micrograms/kg
Paraldehyde rectal or IM 0·4 ml/kg (max 10 ml rectal, 5 ml IM
  at one site)
Epinephrine (adrenaline): 10 micrograms/kg (0·1 ml/kg 1 in
  10 000 or 0·01 ml/kg of 1 in 1000)
Epinephrine: 1 in 1000 = 1 mg/ml: 1 in 10 000 = 100
  micrograms/ml
Fluid resuscitation: 20 ml/kg 0·9% saline or colloid or blood
  (10 ml/kg in neonate)
Frusemide: 1 mg/kg IV
Glucose: 5 ml/kg of 10% IV (0.5 g/kg)

Mannitol: 250–500 mg/kg IV over 20 minutes
Morphine: IV 100 micrograms/kg over 5 minutes (50–100
  micrograms/kg in the neonate)
Salbutamol: 100–1000 micrograms inhaler (1–10 sprays) or
  nebuliser (dose 2·5 mg < 5 years and 5 mg > 5 years)
Salbutamol: IV loading dose = 4–6 micrograms/kg over
  15 minutes monitor ECG and ensure K+ normal
Sodium bicarbonate: 1 mmol/kg (= 2 ml/kg of 4·2%).

Disability
Assessment of neurological function (AVPU) (see page 29 for
  modified Glasgow Coma Scale)
A = alert, V = responds to voice, P = responds to pain, U =
  unresponsive.
Pupillary size and reaction, posture, muscle tone, presence
  of convulsive movements.








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